State of the Art on Approved Cystic Fibrosis Transmembrane Conductance Regulator (<i>CFTR</i>) Modulators and Triple-Combination Therapy

• Главные авторы: Aniello Meoli (Автор), Valentina Fainardi (Автор), Michela Deolmi (Автор), Giulia Chiopris (Автор), Francesca Marinelli (Автор), Caterina Caminiti (Автор), Susanna Esposito (Автор), Giovanna Pisi (Автор)
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• Опубликовано: MDPI AG, 2021-09-01T00:00:00Z.
• Предметы: article
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Cystic fibrosis (CF) is the most common life-limiting inherited disease in Caucasian populations, affecting approximately 80,000 people worldwide. CF is a complex multi-organ monogenic autosomal recessive disorder caused by a mutation in cystic fibrosis transmembrane conductance regulator (<i>...