A modified nucleoside O6-methyl-2'-deoxyguanosine-5'-triphosphate exhibits anti-glioblastoma activity in a caspase-independent manner

• मुख्य लेखकों: Zi-Hui Wang (लेखक), Jin Li (लेखक), Qian Liu (लेखक), Jian-Chang Qian (लेखक), Qing-Qing Li (लेखक), Qing-Yu Wang (लेखक), Lv-Tao Zeng (लेखक), Si-Jia Li (लेखक), Xin Gao (लेखक), Jia-Xin Pan (लेखक), Xu-Fan Gao (लेखक), Kun Wu (लेखक), Guo-Xin Hu (लेखक), Tomoo Iwakuma (लेखक), Jian-Ping Cai (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2024-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Resistance to temozolomide (TMZ), the frontline chemotherapeutic agent for glioblastoma (GBM), has emerged as a formidable obstacle, underscoring the imperative to identify alternative therapeutic strategies to improve patient outcomes. In this study, we comprehensively evaluated a novel agent, O6-m...