A modified nucleoside O6-methyl-2'-deoxyguanosine-5'-triphosphate exhibits anti-glioblastoma activity in a caspase-independent manner

• Váldodahkkit: Zi-Hui Wang (Dahkki), Jin Li (Dahkki), Qian Liu (Dahkki), Jian-Chang Qian (Dahkki), Qing-Qing Li (Dahkki), Qing-Yu Wang (Dahkki), Lv-Tao Zeng (Dahkki), Si-Jia Li (Dahkki), Xin Gao (Dahkki), Jia-Xin Pan (Dahkki), Xu-Fan Gao (Dahkki), Kun Wu (Dahkki), Guo-Xin Hu (Dahkki), Tomoo Iwakuma (Dahkki), Jian-Ping Cai (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Elsevier, 2024-01-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Resistance to temozolomide (TMZ), the frontline chemotherapeutic agent for glioblastoma (GBM), has emerged as a formidable obstacle, underscoring the imperative to identify alternative therapeutic strategies to improve patient outcomes. In this study, we comprehensively evaluated a novel agent, O6-m...