Characterization of Drosophila Saposin-related mutants as a model for lysosomal sphingolipid storage diseases

• Asıl Yazarlar: Julia Sellin (Yazar), Heike Schulze (Yazar), Marie Paradis (Yazar), Dominic Gosejacob (Yazar), Cyrus Papan (Yazar), Andrej Shevchenko (Yazar), Olympia Ekaterina Psathaki (Yazar), Achim Paululat (Yazar), Melanie Thielisch (Yazar), Konrad Sandhoff (Yazar), Michael Hoch (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: The Company of Biologists, 2017-06-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Sphingolipidoses are inherited diseases belonging to the class of lysosomal storage diseases (LSDs), which are characterized by the accumulation of indigestible material in the lysosome caused by specific defects in the lysosomal degradation machinery. While some LSDs can be efficiently treated by e...