Characterization of Drosophila Saposin-related mutants as a model for lysosomal sphingolipid storage diseases

• প্রধান লেখক: Julia Sellin (লেখক), Heike Schulze (লেখক), Marie Paradis (লেখক), Dominic Gosejacob (লেখক), Cyrus Papan (লেখক), Andrej Shevchenko (লেখক), Olympia Ekaterina Psathaki (লেখক), Achim Paululat (লেখক), Melanie Thielisch (লেখক), Konrad Sandhoff (লেখক), Michael Hoch (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: The Company of Biologists, 2017-06-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Sphingolipidoses are inherited diseases belonging to the class of lysosomal storage diseases (LSDs), which are characterized by the accumulation of indigestible material in the lysosome caused by specific defects in the lysosomal degradation machinery. While some LSDs can be efficiently treated by e...