Nose-to-brain delivery of macromolecules mediated by cell-penetrating peptides

• Main Authors: Tingting Lin (Author), Ergang Liu (Author), Huining He (Author), Meong Cheol Shin (Author), Cheol Moon (Author), Victor C. Yang (Author), Yongzhuo Huang (Author)
• Format: Book
• Published: Elsevier, 2016-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Brain delivery of macromolecular therapeutics (e.g., proteins) remains an unsolved problem because of the formidable blood-brain barrier (BBB). Although a direct pathway of nose-to-brain transfer provides an answer to circumventing the BBB and has already been intensively investigated for brain deli...