Nose-to-brain delivery of macromolecules mediated by cell-penetrating peptides

• Główni autorzy: Tingting Lin (Autor), Ergang Liu (Autor), Huining He (Autor), Meong Cheol Shin (Autor), Cheol Moon (Autor), Victor C. Yang (Autor), Yongzhuo Huang (Autor)
• Format: Książka
• Wydane: Elsevier, 2016-07-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Brain delivery of macromolecular therapeutics (e.g., proteins) remains an unsolved problem because of the formidable blood-brain barrier (BBB). Although a direct pathway of nose-to-brain transfer provides an answer to circumventing the BBB and has already been intensively investigated for brain deli...