Nose-to-brain delivery of macromolecules mediated by cell-penetrating peptides

• Egile Nagusiak: Tingting Lin (Egilea), Ergang Liu (Egilea), Huining He (Egilea), Meong Cheol Shin (Egilea), Cheol Moon (Egilea), Victor C. Yang (Egilea), Yongzhuo Huang (Egilea)
• Formatua: Liburua
• Argitaratua: Elsevier, 2016-07-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Brain delivery of macromolecular therapeutics (e.g., proteins) remains an unsolved problem because of the formidable blood-brain barrier (BBB). Although a direct pathway of nose-to-brain transfer provides an answer to circumventing the BBB and has already been intensively investigated for brain deli...