Overcoming Resistance to Immune Checkpoint Inhibitor Therapy Using Calreticulin-Inducing Nanoparticle

• Hoofdauteurs: Sri Vidhya Chandrasekar (Auteur), Akansha Singh (Auteur), Ashish Ranjan (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2023-06-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Nanoparticles (NPs) have the ability to transform poorly immunogenic tumors into activated 'hot' targets. In this study, we investigated the potential of a liposome-based nanoparticle (CRT-NP) expressing calreticulin as an in-situ vaccine to restore sensitivity to anti-CTLA4 immune checkpo...