A novel hybrid aspirin-NO-releasing compound inhibits TNFalpha release from LPS-activated human monocytes and macrophages

• Váldodahkkit: Fox Sarah (Dahkki), Gasco Alberto (Dahkki), Fruttero Roberta (Dahkki), Cena Clara (Dahkki), Lazzarato Loretta (Dahkki), Sheldrake Tara A (Dahkki), Marcarino Paolo (Dahkki), Turnbull Catriona M (Dahkki), Megson Ian L (Dahkki), Rossi Adriano G (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: BMC, 2008-07-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>The cytoprotective nature of nitric oxide (NO) led to development of NO-aspirins in the hope of overcoming the gastric side-effects of aspirin. However, the NO moiety gives these hybrids potential for actions further to their aspirin...