Discovery of benzochalcone derivative as a potential antigastric cancer agent targeting signal transducer and activator of transcription 3 (STAT3)

• Main Authors: Jinyun Dong (Author), Jing Yang (Author), Wenkai Yu (Author), Haobin Li (Author), Maohua Cai (Author), Jing-Li Xu (Author), Han-Dong Xu (Author), Yun-Fu Shi (Author), Xiaoqing Guan (Author), Xiang‑Dong Cheng (Author), Jiang‑Jiang Qin (Author)
• Format: Book
• Published: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Gastric cancer remains a significant health burden worldwide. In continuation of our previous study and development of effective small molecules against gastric cancer, a series of benzochalcone analogues involving heterocyclic molecules were synthesised and biologically evaluated in vitro and in vi...