Discovery of benzochalcone derivative as a potential antigastric cancer agent targeting signal transducer and activator of transcription 3 (STAT3)

• Hoofdauteurs: Jinyun Dong (Auteur), Jing Yang (Auteur), Wenkai Yu (Auteur), Haobin Li (Auteur), Maohua Cai (Auteur), Jing-Li Xu (Auteur), Han-Dong Xu (Auteur), Yun-Fu Shi (Auteur), Xiaoqing Guan (Auteur), Xiang‑Dong Cheng (Auteur), Jiang‑Jiang Qin (Auteur)
• Formaat: Boek
• Gepubliceerd in: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Gastric cancer remains a significant health burden worldwide. In continuation of our previous study and development of effective small molecules against gastric cancer, a series of benzochalcone analogues involving heterocyclic molecules were synthesised and biologically evaluated in vitro and in vi...