Impaired Surface Expression of HLA-DR, TLR2, TLR4, and TLR9 in Ex Vivo-In Vitro Stimulated Monocytes from Severely Injured Trauma Patients

• Asıl Yazarlar: David Heftrig (Yazar), Ramona Sturm (Yazar), Elsie Oppermann (Yazar), Kerstin Kontradowitz (Yazar), Katrin Jurida (Yazar), Lukas Schimunek (Yazar), Mathias Woschek (Yazar), Ingo Marzi (Yazar), Borna Relja (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Hindawi Limited, 2017-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Objective. Trauma patients (TP) frequently develop an imbalanced immune response that often causes infectious postinjury complications. Monocytes show a diminished capability of both producing proinflammatory cytokines and antigen presentation after trauma. TLR2, TLR4, and TLR9 recognize pathogens a...