Development of small molecule extracellular signal-regulated kinases (ERKs) inhibitors for cancer therapy

• Auteurs principaux: Xiaoli Pan (Auteur), Junping Pei (Auteur), Aoxue Wang (Auteur), Wen Shuai (Auteur), Lu Feng (Auteur), Faqian Bu (Auteur), Yumeng Zhu (Auteur), Lan Zhang (Auteur), Guan Wang (Auteur), Liang Ouyang (Auteur)
• Format: Livre
• Publié: Elsevier, 2022-05-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

The mitogen-activated protein kinase (MAPK)/extracellular signal-regulated kinase 1/2 (ERK1/2) signaling pathway is widely activated by a variety of extracellular stimuli, and its dysregulation is associated with the proliferation, invasion, and migration of cancer cells. ERK1/2 is located at the di...