Development of small molecule extracellular signal-regulated kinases (ERKs) inhibitors for cancer therapy

• Main Authors: Xiaoli Pan (Author), Junping Pei (Author), Aoxue Wang (Author), Wen Shuai (Author), Lu Feng (Author), Faqian Bu (Author), Yumeng Zhu (Author), Lan Zhang (Author), Guan Wang (Author), Liang Ouyang (Author)
• Format: Book
• Published: Elsevier, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The mitogen-activated protein kinase (MAPK)/extracellular signal-regulated kinase 1/2 (ERK1/2) signaling pathway is widely activated by a variety of extracellular stimuli, and its dysregulation is associated with the proliferation, invasion, and migration of cancer cells. ERK1/2 is located at the di...