Neuropilin-1highCD4+CD25+ Regulatory T Cells Exhibit Primary Negative Immunoregulation in Sepsis

• Hoofdauteurs: Yu-Lei Gao (Auteur), Yan-Fen Chai (Auteur), An-Long Qi (Auteur), Ying Yao (Auteur), Yan-Cun Liu (Auteur), Ning Dong (Auteur), Li-Jun Wang (Auteur), Yong-Ming Yao (Auteur)
• Formaat: Boek
• Gepubliceerd in: Hindawi Limited, 2016-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Regulatory T cells (Tregs) appear to be involved in sepsis-induced immune dysfunction; neuropilin-1 (Nrp-1) was identified as a surface marker for CD4+CD25+Tregs. In the current study, we investigated the negative immunoregulation of Nrp-1highCD4+CD25+Tregs and the potential therapeutic value of Nrp...