Neuropilin-1highCD4+CD25+ Regulatory T Cells Exhibit Primary Negative Immunoregulation in Sepsis

• Váldodahkkit: Yu-Lei Gao (Dahkki), Yan-Fen Chai (Dahkki), An-Long Qi (Dahkki), Ying Yao (Dahkki), Yan-Cun Liu (Dahkki), Ning Dong (Dahkki), Li-Jun Wang (Dahkki), Yong-Ming Yao (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Hindawi Limited, 2016-01-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Regulatory T cells (Tregs) appear to be involved in sepsis-induced immune dysfunction; neuropilin-1 (Nrp-1) was identified as a surface marker for CD4+CD25+Tregs. In the current study, we investigated the negative immunoregulation of Nrp-1highCD4+CD25+Tregs and the potential therapeutic value of Nrp...