Neuropilin-1highCD4+CD25+ Regulatory T Cells Exhibit Primary Negative Immunoregulation in Sepsis

• Autori principali: Yu-Lei Gao (Autore), Yan-Fen Chai (Autore), An-Long Qi (Autore), Ying Yao (Autore), Yan-Cun Liu (Autore), Ning Dong (Autore), Li-Jun Wang (Autore), Yong-Ming Yao (Autore)
• Natura: Libro
• Pubblicazione: Hindawi Limited, 2016-01-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Regulatory T cells (Tregs) appear to be involved in sepsis-induced immune dysfunction; neuropilin-1 (Nrp-1) was identified as a surface marker for CD4+CD25+Tregs. In the current study, we investigated the negative immunoregulation of Nrp-1highCD4+CD25+Tregs and the potential therapeutic value of Nrp...