Impact of obesity and roux‐en‐Y gastric bypass on the pharmacokinetics of (R)‐ and (S)‐omeprazole and intragastric pH

Abstract This study employed physiologically‐based pharmacokinetic-pharmacodynamics (PBPK/PD) modeling to predict the effect of obesity and gastric bypass surgery on the pharmacokinetics and intragastric pH following omeprazole treatment. The simulated plasma concentrations closely matched the obser...

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Asıl Yazarlar: Leandro F. Pippa (Yazar), Valvanera Vozmediano (Yazar), Lieke Mitrov‐Winkelmolen (Yazar), Daan Touw (Yazar), Amira Soliman (Yazar), Rodrigo Cristofoletti (Yazar), Wilson Salgado Junior (Yazar), Natalia Valadares de Moraes (Yazar)
Materyal Türü: Kitap
Baskı/Yayın Bilgisi: Wiley, 2024-09-01T00:00:00Z.
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3rd Floor Main Library

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Yer Numarası: A1234.567
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