A complement component C1q-mediated mechanism of antibody-dependent enhancement of Ebola virus infection.

• Główni autorzy: Wakako Furuyama (Autor), Asuka Nanbo (Autor), Junki Maruyama (Autor), Andrea Marzi (Autor), Ayato Takada (Autor)
• Format: Książka
• Wydane: Public Library of Science (PLoS), 2020-09-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Besides the common Fc receptor (FcR)-mediated mechanism of antibody-dependent enhancement (ADE), Ebola virus (EBOV) is known to utilize the complement component C1q for ADE of infection. This mechanism is FcR-independent and mediated by cross-linking of virus-antibody-C1q complexes to cell surface C...