A complement component C1q-mediated mechanism of antibody-dependent enhancement of Ebola virus infection.

• Главные авторы: Wakako Furuyama (Автор), Asuka Nanbo (Автор), Junki Maruyama (Автор), Andrea Marzi (Автор), Ayato Takada (Автор)
• Формат: ‌
• Опубликовано: Public Library of Science (PLoS), 2020-09-01T00:00:00Z.
• Предметы: article
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Besides the common Fc receptor (FcR)-mediated mechanism of antibody-dependent enhancement (ADE), Ebola virus (EBOV) is known to utilize the complement component C1q for ADE of infection. This mechanism is FcR-independent and mediated by cross-linking of virus-antibody-C1q complexes to cell surface C...