Cold temperature improves mobility and survival in Drosophila models of autosomal-dominant hereditary spastic paraplegia (AD-HSP)

• Asıl Yazarlar: Sally L. Baxter (Yazar), Denise E. Allard (Yazar), Christopher Crowl (Yazar), Nina Tang Sherwood (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: The Company of Biologists, 2014-08-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Autosomal-dominant hereditary spastic paraplegia (AD-HSP) is a crippling neurodegenerative disease for which effective treatment or cure remains unknown. Victims experience progressive mobility loss due to degeneration of the longest axons in the spinal cord. Over half of AD-HSP cases arise from los...