Cold temperature improves mobility and survival in Drosophila models of autosomal-dominant hereditary spastic paraplegia (AD-HSP)

• Hoofdauteurs: Sally L. Baxter (Auteur), Denise E. Allard (Auteur), Christopher Crowl (Auteur), Nina Tang Sherwood (Auteur)
• Formaat: Boek
• Gepubliceerd in: The Company of Biologists, 2014-08-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Autosomal-dominant hereditary spastic paraplegia (AD-HSP) is a crippling neurodegenerative disease for which effective treatment or cure remains unknown. Victims experience progressive mobility loss due to degeneration of the longest axons in the spinal cord. Over half of AD-HSP cases arise from los...