In vitro - in vivo - in silico approach in the development of inhaled drug products: Nanocrystal-based formulations with budesonide as a model drug

• Auteurs principaux: Changzhi Shi (Auteur), Jelisaveta Ignjatović (Auteur), Tingting Liu (Auteur), Meihua Han (Auteur), Dongmei Cun (Auteur), Jelena Đuriš (Auteur), Mingshi Yang (Auteur), Sandra Cvijić (Auteur)
• Format: Livre
• Publié: Elsevier, 2021-05-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

This study aims to understand the absorption patterns of three different kinds of inhaled formulations via in silico modeling using budesonide (BUD) as a model drug. The formulations investigated in this study are: (i) commercially available micronized BUD mixed with lactose (BUD-PT), (ii) BUD nanoc...