A double-hit pre-eclampsia model results in sex-specific growth restriction patterns

• Main Authors: Violeta Stojanovska (Author), Dorieke J. Dijkstra (Author), Rebekka Vogtmann (Author), Alexandra Gellhaus (Author), Sicco A. Scherjon (Author), Torsten Plösch (Author)
• Formato: Livro
• Publicado em: The Company of Biologists, 2019-02-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Pre-eclampsia is a multifactorial pregnancy-associated disorder characterized by angiogenic dysbalance and systemic inflammation; however, animal models that combine these two pathophysiological conditions are missing. Here, we introduce a novel double-hit pre-eclampsia mouse model that mimics the c...