Activation of NRF2 Signaling Pathway Delays the Progression of Hyperuricemic Nephropathy by Reducing Oxidative Stress

• Главные авторы: Panshuang Qiao (Автор), Yi Sun (Автор), Yiming Wang (Автор), Simei Lin (Автор), Yongpan An (Автор), Liang Wang (Автор), Jihan Liu (Автор), Yajun Huang (Автор), Baoxue Yang (Автор), Hong Zhou (Автор)
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• Опубликовано: MDPI AG, 2023-04-01T00:00:00Z.
• Предметы: article
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Hyperuricemia (HUA)-induced oxidative stress is a crucial contributor to hyperuricemic nephropathy (HN), but the molecular mechanisms underlying the disturbed redox homeostasis in kidneys remain elusive. Using RNA sequencing, together with biochemical analyses, we found that nuclear factor erythroid...