Dimeric Lectin Chimeras as Novel Candidates for Gb3-Mediated Transcytotic Drug Delivery through Cellular Barriers

Dimeric Lectin Chimeras as Novel Candidates for Gb3-Mediated Transcytotic Drug Delivery through Cellular Barriers

Receptor-mediated transcytosis is an elegant and promising strategy for drug delivery across biological barriers. Here, we describe a novel ligand-receptor pair based on a dimeric, engineered derivative of the <i>Pseudomonas aeruginosa</i> lectin LecA, here termed Di-LecA, and the host c...

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Main Authors: Maokai Xu (Author), Maria Antonova (Author), Pavel Salavei (Author), Katharina Illek (Author), Ana Valeria Meléndez (Author), Ramin Omidvar (Author), Roland Thuenauer (Author), Olga Makshakova (Author), Winfried Römer (Author)
Format: Book
Published: MDPI AG, 2023-01-01T00:00:00Z.
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