Phospholamban overexpression in mice causes a centronuclear myopathy-like phenotype

• 主要な著者: Val A. Fajardo (著者), Eric Bombardier (著者), Elliott McMillan (著者), Khanh Tran (著者), Brennan J. Wadsworth (著者), Daniel Gamu (著者), Andrew Hopf (著者), Chris Vigna (著者), Ian C. Smith (著者), Catherine Bellissimo (著者), Robin N. Michel (著者), Mark A. Tarnopolsky (著者), Joe Quadrilatero (著者), A. Russell Tupling (著者)
• フォーマット: 図書
• 出版事項: The Company of Biologists, 2015-08-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Centronuclear myopathy (CNM) is a congenital myopathy that is histopathologically characterized by centrally located nuclei, central aggregation of oxidative activity, and type I fiber predominance and hypotrophy. Here, we obtained commercially available mice overexpressing phospholamban (PlnOE), a...