Hemisynthesis and Biological Evaluation of Cinnamylated, Benzylated, and Prenylated Dihydrochalcones from a Common Bio-Sourced Precursor

• Autori principali: Anne Ardaillou (Autore), Jérôme Alsarraf (Autore), Jean Legault (Autore), François Simard (Autore), André Pichette (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2021-05-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Several families of naturally occurring <i>C</i>-alkylated dihydrochalcones display a broad range of biological activities, including antimicrobial and cytotoxic properties, depending on their alkylation sidechain. The catalytic Friedel-Crafts alkylation of the readily available aglycon...