Hemisynthesis and Biological Evaluation of Cinnamylated, Benzylated, and Prenylated Dihydrochalcones from a Common Bio-Sourced Precursor

• Main Authors: Anne Ardaillou (Author), Jérôme Alsarraf (Author), Jean Legault (Author), François Simard (Author), André Pichette (Author)
• 格式: 圖書
• 出版: MDPI AG, 2021-05-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

Several families of naturally occurring <i>C</i>-alkylated dihydrochalcones display a broad range of biological activities, including antimicrobial and cytotoxic properties, depending on their alkylation sidechain. The catalytic Friedel-Crafts alkylation of the readily available aglycon...