Attenuation of toll-like receptor expression and function in latent tuberculosis by coexistent filarial infection with restoration following antifilarial chemotherapy.

• Autori principali: Subash Babu (Autore), Sajid Q Bhat (Autore), N Pavan Kumar (Autore), R Anuradha (Autore), Paul Kumaran (Autore), P G Gopi (Autore), C Kolappan (Autore), V Kumaraswami (Autore), Thomas B Nutman (Autore)
• Natura: Libro
• Pubblicazione: Public Library of Science (PLoS), 2009-07-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Mycobacterium tuberculosis (Mtb) and filarial coinfection is highly prevalent, and the presence of filarial infections may regulate the Toll-like receptor (TLR)-dependent immune response needed to control Mtb infection. By analyzing the baseline and mycobacterial antigen-stimulated expression of TLR...