Phosphatidylinositol 3-kinase-δ (PI3K-δ) is a potential therapeutic target in adult T-cell leukemia-lymphoma

• Κύριοι συγγραφείς: Hiroo Katsuya (Συγγραφέας), Lucy B. M. Cook (Συγγραφέας), Aileen G. Rowan (Συγγραφέας), Yorifumi Satou (Συγγραφέας), Graham P. Taylor (Συγγραφέας), Charles R. M. Bangham (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: BMC, 2018-07-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Abstract The prognosis of adult T-cell leukemia-lymphoma (ATL) remains very poor, and there is an urgent clinical need to investigate novel therapies for ATL. The expression of phosphatidylinositol 3-kinase-δ (PI3k-δ) is normally restricted to hematopoietic cells and is known as a key determinant of...