Orthogonal quantification of soluble inducible T-cell costimulator (ICOS) in healthy and diseased human serum

• Príomhchruthaitheoirí: Kevin McKinski (Údar), Dean McNulty (Údar), Francesca Zappacosta (Údar), Mary Birchler (Údar), Matt Szapacs (Údar), Christopher Evans (Údar)
• Formáid: LEABHAR
• Foilsithe / Cruthaithe: Elsevier, 2022-04-01T00:00:00Z.
• Ábhair: article
• Rochtain ar líne: Connect to this object online.

Inducible T-cell costimulator (ICOS), a homodimeric protein expressed on the surface of activated T-cells, is being investigated as a potential therapeutic target to treat various cancers. Recent studies have reported aberrant increases in the soluble form of ICOS (sICOS) in human serum in disease-s...