Perturbation of the titin/MURF1 signaling complex is associated with hypertrophic cardiomyopathy in a fish model and in human patients

• Үндсэн зохиолчид: Yuta Higashikuse (Зохиогч), Nishant Mittal (Зохиогч), Takuro Arimura (Зохиогч), Sung Han Yoon (Зохиогч), Mayumi Oda (Зохиогч), Hirokazu Enomoto (Зохиогч), Ruri Kaneda (Зохиогч), Fumiyuki Hattori (Зохиогч), Takeshi Suzuki (Зохиогч), Atsushi Kawakami (Зохиогч), Alexander Gasch (Зохиогч), Tetsushi Furukawa (Зохиогч), Siegfried Labeit (Зохиогч), Keiichi Fukuda (Зохиогч), Akinori Kimura (Зохиогч), Shinji Makino (Зохиогч)
• Формат: Ном
• Хэвлэсэн: The Company of Biologists, 2019-11-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Hypertrophic cardiomyopathy (HCM) is a hereditary disease characterized by cardiac hypertrophy with diastolic dysfunction. Gene mutations causing HCM have been found in about half of HCM patients, while the genetic etiology and pathogenesis remain unknown for many cases of HCM. To identify novel mec...