Identification and Pharmaceutical Characterization of a New Itraconazole Terephthalic Acid Cocrystal

• Prif Awduron: Ricardo Machado Cruz (Awdur), Tereza Boleslavská (Awdur), Josef Beránek (Awdur), Eszter Tieger (Awdur), Brendan Twamley (Awdur), Maria Jose Santos-Martinez (Awdur), Ondřej Dammer (Awdur), Lidia Tajber (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: MDPI AG, 2020-08-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

The crystallization of poorly soluble drug molecules with an excipient into new solid phases called cocrystals has gained a considerable popularity in the pharmaceutical field. In this work, the cocrystal approach was explored for a very poorly water soluble antifungal active, itraconazole (ITR), wh...