In Vitro Stimulation of Multidrug Resistance-Associated Protein 2 Function Is Not Reproduced In Vivo in Rats

• Hoofdauteurs: Ravindranath Reddy Gilibili (Auteur), Vishwanath Kurawattimath (Auteur), Bokka Venkata Murali (Auteur), Yurong Lai (Auteur), T. Thanga Mariappan (Auteur), Hong Shen (Auteur), Sagnik Chatterjee (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2018-08-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Previously we reported that coproporphyrin-I (CP-I) is an optimal probe substrate for multidrug resistance-associated protein 2 (MRP2), and stimulation of MRP2-mediated transport is probe substrate-dependent. In the present investigation, we assessed if the in vitro stimulation is physiologically re...