Hyper-Branched Cationic Cyclodextrin Polymers for Improving Plasmid Transfection in 2D and 3D Spheroid Cells

• Main Authors: Yousef Khazaei Monfared (Author), Mohammad Mahmoudian (Author), Claudio Cecone (Author), Fabrizio Caldera (Author), Sanya Haiaty (Author), Hamid Reza Heidari (Author), Reza Rahbarghazi (Author), Adrián Matencio (Author), Parvin Zakeri-Milani (Author), Francesco Trotta (Author)
• Format: Book
• Published: MDPI AG, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In this article, we used monolayer two dimensional (2D) and 3D multicellular spheroid models to improve our understanding of the gene delivery process of a new modified cationic hyper-branched cyclodextrin-based polymer (Ppoly)-loaded plasmid encoding Enhanced Green Fluorescent Protein (EGFP). A com...