Hyper-Branched Cationic Cyclodextrin Polymers for Improving Plasmid Transfection in 2D and 3D Spheroid Cells

• Autori principali: Yousef Khazaei Monfared (Autore), Mohammad Mahmoudian (Autore), Claudio Cecone (Autore), Fabrizio Caldera (Autore), Sanya Haiaty (Autore), Hamid Reza Heidari (Autore), Reza Rahbarghazi (Autore), Adrián Matencio (Autore), Parvin Zakeri-Milani (Autore), Francesco Trotta (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2022-12-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

In this article, we used monolayer two dimensional (2D) and 3D multicellular spheroid models to improve our understanding of the gene delivery process of a new modified cationic hyper-branched cyclodextrin-based polymer (Ppoly)-loaded plasmid encoding Enhanced Green Fluorescent Protein (EGFP). A com...