Applicability of generic assays based on liquid chromatography-electrospray mass spectrometry to study in vitro metabolism of 55 structurally diverse compounds
Liquid chromatography-mass spectrometry (LC/MS) with generic gradient elution for a large number of chemically different compounds is a common approach in drug development, used to acquire a large amount of data in a short time frame for drug candidates. The analysis with non-optimised parameters ho...
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Frontiers Media S.A.,
2010-08-01T00:00:00Z.
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