MCC1019, a selective inhibitor of the Polo-box domain of Polo-like kinase 1 as novel, potent anticancer candidate
Polo-like kinase (PLK1) has been identified as a potential target for cancer treatment. Although a number of small molecules have been investigated as PLK1 inhibitors, many of which showed limited selectivity. PLK1 harbors a regulatory domain, the Polo box domain (PBD), which has a key regulatory fu...
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मुख्य लेखकों: | , , , , , , , , , , |
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स्वरूप: | पुस्तक |
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Elsevier,
2019-09-01T00:00:00Z.
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A1234.567 |
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प्रति 1 | उपलब्ध |