Targeting IgG Autoantibodies for Improved Cytotoxicity of Bactericidal Permeability Increasing Protein in Cystic Fibrosis

• Hauptverfasser: Karen McQuillan (Verfasst von), Fatma Gargoum (Verfasst von), Mark P. Murphy (Verfasst von), Oliver J. McElvaney (Verfasst von), Noel G. McElvaney (Verfasst von), Emer P. Reeves (Verfasst von)
• Format: Buch
• Veröffentlicht: Frontiers Media S.A., 2020-07-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

In people with cystic fibrosis (PWCF), inflammation with concurrent infection occurs from a young age and significantly influences lung disease progression. Studies indicate that neutrophils are important effector cells in the pathogenesis of CF and in the development of anti-neutrophil cytoplasmic...