Targeting IgG Autoantibodies for Improved Cytotoxicity of Bactericidal Permeability Increasing Protein in Cystic Fibrosis

• Glavni autori: Karen McQuillan (Autor), Fatma Gargoum (Autor), Mark P. Murphy (Autor), Oliver J. McElvaney (Autor), Noel G. McElvaney (Autor), Emer P. Reeves (Autor)
• Format: Knjiga
• Izdano: Frontiers Media S.A., 2020-07-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

In people with cystic fibrosis (PWCF), inflammation with concurrent infection occurs from a young age and significantly influences lung disease progression. Studies indicate that neutrophils are important effector cells in the pathogenesis of CF and in the development of anti-neutrophil cytoplasmic...