Targeting IgG Autoantibodies for Improved Cytotoxicity of Bactericidal Permeability Increasing Protein in Cystic Fibrosis

• Главные авторы: Karen McQuillan (Автор), Fatma Gargoum (Автор), Mark P. Murphy (Автор), Oliver J. McElvaney (Автор), Noel G. McElvaney (Автор), Emer P. Reeves (Автор)
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• Опубликовано: Frontiers Media S.A., 2020-07-01T00:00:00Z.
• Предметы: article
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In people with cystic fibrosis (PWCF), inflammation with concurrent infection occurs from a young age and significantly influences lung disease progression. Studies indicate that neutrophils are important effector cells in the pathogenesis of CF and in the development of anti-neutrophil cytoplasmic...