2-Phenoxy-3-Trichloromethylquinoxalines Are Antiplasmodial Derivatives with Activity against the Apicoplast of <i>Plasmodium falciparum</i>

The malaria parasite harbors a relict plastid called the apicoplast. Although not photosynthetic, the apicoplast retains unusual, non-mammalian metabolic pathways that are essential to the parasite, opening up a new perspective for the development of novel antimalarials which display a new mechanism...

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Main Authors: Dyhia Amrane (Author), Christophe-Sébastien Arnold (Author), Sébastien Hutter (Author), Julen Sanz-Serrano (Author), Miguel Collia (Author), Amaya Azqueta (Author), Lucie Paloque (Author), Anita Cohen (Author), Nadia Amanzougaghene (Author), Shahin Tajeri (Author), Jean-François Franetich (Author), Dominique Mazier (Author), Françoise Benoit-Vical (Author), Pierre Verhaeghe (Author), Nadine Azas (Author), Patrice Vanelle (Author), Cyrille Botté (Author), Nicolas Primas (Author)
Format: Book
Published: MDPI AG, 2021-07-01T00:00:00Z.
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