2-Phenoxy-3-Trichloromethylquinoxalines Are Antiplasmodial Derivatives with Activity against the Apicoplast of <i>Plasmodium falciparum</i>

• প্রধান লেখক: Dyhia Amrane (লেখক), Christophe-Sébastien Arnold (লেখক), Sébastien Hutter (লেখক), Julen Sanz-Serrano (লেখক), Miguel Collia (লেখক), Amaya Azqueta (লেখক), Lucie Paloque (লেখক), Anita Cohen (লেখক), Nadia Amanzougaghene (লেখক), Shahin Tajeri (লেখক), Jean-François Franetich (লেখক), Dominique Mazier (লেখক), Françoise Benoit-Vical (লেখক), Pierre Verhaeghe (লেখক), Nadine Azas (লেখক), Patrice Vanelle (লেখক), Cyrille Botté (লেখক), Nicolas Primas (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: MDPI AG, 2021-07-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

The malaria parasite harbors a relict plastid called the apicoplast. Although not photosynthetic, the apicoplast retains unusual, non-mammalian metabolic pathways that are essential to the parasite, opening up a new perspective for the development of novel antimalarials which display a new mechanism...