The macrocyclic lactone oxacyclododecindione reduces fibrosis progression

• Hlavní autoři: Sabrina Saurin (Autor), Myriam Meineck (Autor), Markus Rohr (Autor), Wilfried Roth (Autor), Till Opatz (Autor), Gerhard Erkel (Autor), Andrea Pautz (Autor), Julia Weinmann-Menke (Autor)
• Médium: Kniha
• Vydáno: Frontiers Media S.A., 2023-06-01T00:00:00Z.
• Témata: article
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Background: Renal fibrosis is one of the most important triggers of chronic kidney disease (CKD), and only a very limited number of therapeutic options are available to stop fibrosis progression. As fibrosis is characterized by inflammation, myofibroblast activation, and extracellular matrix (ECM) d...