The macrocyclic lactone oxacyclododecindione reduces fibrosis progression

• मुख्य लेखकों: Sabrina Saurin (लेखक), Myriam Meineck (लेखक), Markus Rohr (लेखक), Wilfried Roth (लेखक), Till Opatz (लेखक), Gerhard Erkel (लेखक), Andrea Pautz (लेखक), Julia Weinmann-Menke (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2023-06-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Background: Renal fibrosis is one of the most important triggers of chronic kidney disease (CKD), and only a very limited number of therapeutic options are available to stop fibrosis progression. As fibrosis is characterized by inflammation, myofibroblast activation, and extracellular matrix (ECM) d...