The macrocyclic lactone oxacyclododecindione reduces fibrosis progression

• Main Authors: Sabrina Saurin (Author), Myriam Meineck (Author), Markus Rohr (Author), Wilfried Roth (Author), Till Opatz (Author), Gerhard Erkel (Author), Andrea Pautz (Author), Julia Weinmann-Menke (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Renal fibrosis is one of the most important triggers of chronic kidney disease (CKD), and only a very limited number of therapeutic options are available to stop fibrosis progression. As fibrosis is characterized by inflammation, myofibroblast activation, and extracellular matrix (ECM) d...