Enzymatic Metabolic Switches of Astrocyte Response to Lipotoxicity as Potential Therapeutic Targets for Nervous System Diseases

• Main Authors: Andrea Angarita-Rodríguez (Author), J. Manuel Matiz-González (Author), Andrés Pinzón (Author), Andrés Felipe Aristizabal (Author), David Ramírez (Author), George E. Barreto (Author), Janneth González (Author)
• Format: Book
• Published: MDPI AG, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Astrocytes play a pivotal role in maintaining brain homeostasis. Recent research has highlighted the significance of palmitic acid (PA) in triggering pro-inflammatory pathways contributing to neurotoxicity. Furthermore, Genomic-scale metabolic models and control theory have revealed that metabolic s...