Enzymatic Metabolic Switches of Astrocyte Response to Lipotoxicity as Potential Therapeutic Targets for Nervous System Diseases

• Autori principali: Andrea Angarita-Rodríguez (Autore), J. Manuel Matiz-González (Autore), Andrés Pinzón (Autore), Andrés Felipe Aristizabal (Autore), David Ramírez (Autore), George E. Barreto (Autore), Janneth González (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2024-05-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Astrocytes play a pivotal role in maintaining brain homeostasis. Recent research has highlighted the significance of palmitic acid (PA) in triggering pro-inflammatory pathways contributing to neurotoxicity. Furthermore, Genomic-scale metabolic models and control theory have revealed that metabolic s...