IRAK4 inhibition: an effective strategy for immunomodulating peri-implant osseointegration via reciprocally-shifted polarization in the monocyte-macrophage lineage cells

Abstract Background The biomaterial integration depends on its interaction with the host immune system. Monocyte-macrophage lineage cells are immediately recruited to the implant site, polarized into different phenotypes, and fused into multinucleated cells, thus playing roles in tissue regeneration...

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Main Authors: Juan Zhao (Author), Jia Li (Author), Antian Xu (Author), Yangbo Xu (Author), Fuming He (Author), Yingjie Mao (Author)
Format: Book
Published: BMC, 2023-05-01T00:00:00Z.
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3rd Floor Main Library

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