Case Report: DOCK8 Deficiency Without Hyper-IgE in a Child With a Large Deletion

• Główni autorzy: Edna Venegas-Montoya (Autor), Aidé Tamara Staines-Boone (Autor), Luz María Sánchez-Sánchez (Autor), Jorge Alberto García-Campos (Autor), Rubén Antonio Córdova-Gurrola (Autor), Yuridia Salazar-Galvez (Autor), David Múzquiz-Zermeño (Autor), María Edith González-Serrano (Autor), Saul O. Lugo Reyes (Autor)
• Format: Książka
• Wydane: Frontiers Media S.A., 2021-06-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Autosomal recessive (AR) DOCK8 deficiency is a well-known actinopathy, a combined primary immune deficiency with impaired actin polymerization that results in altered cell mobility and immune synapse. DOCK8-deficient patients present early in life with eczema, viral cutaneous infections, chronic muc...