Case Report: DOCK8 Deficiency Without Hyper-IgE in a Child With a Large Deletion

• প্রধান লেখক: Edna Venegas-Montoya (লেখক), Aidé Tamara Staines-Boone (লেখক), Luz María Sánchez-Sánchez (লেখক), Jorge Alberto García-Campos (লেখক), Rubén Antonio Córdova-Gurrola (লেখক), Yuridia Salazar-Galvez (লেখক), David Múzquiz-Zermeño (লেখক), María Edith González-Serrano (লেখক), Saul O. Lugo Reyes (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Frontiers Media S.A., 2021-06-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Autosomal recessive (AR) DOCK8 deficiency is a well-known actinopathy, a combined primary immune deficiency with impaired actin polymerization that results in altered cell mobility and immune synapse. DOCK8-deficient patients present early in life with eczema, viral cutaneous infections, chronic muc...