LINC00460-miR-149-5p/miR-150-5p-Mutant p53 Feedback Loop Promotes Oxaliplatin Resistance in Colorectal Cancer

• Auteurs principaux: Xiangfeng Meng (Auteur), Wu Sun (Auteur), Jing Yu (Auteur), Yu Zhou (Auteur), Yuanyuan Gu (Auteur), Jiayi Han (Auteur), Likun Zhou (Auteur), Xiaohong Jiang (Auteur), Chen Wang (Auteur)
• Format: Livre
• Publié: Elsevier, 2020-12-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Oxaliplatin resistance is a major challenge in the clinical treatment for advanced colorectal cancer (CRC). Long non-coding RNAs (lncRNAs) are involved in tumorigenesis and progression as critical regulators, while their potential roles in chemoresistance are poorly understood. In this study, we rep...