LINC00460-miR-149-5p/miR-150-5p-Mutant p53 Feedback Loop Promotes Oxaliplatin Resistance in Colorectal Cancer

• Autores principales: Xiangfeng Meng (Autor), Wu Sun (Autor), Jing Yu (Autor), Yu Zhou (Autor), Yuanyuan Gu (Autor), Jiayi Han (Autor), Likun Zhou (Autor), Xiaohong Jiang (Autor), Chen Wang (Autor)
• Formato: Libro
• Publicado: Elsevier, 2020-12-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Oxaliplatin resistance is a major challenge in the clinical treatment for advanced colorectal cancer (CRC). Long non-coding RNAs (lncRNAs) are involved in tumorigenesis and progression as critical regulators, while their potential roles in chemoresistance are poorly understood. In this study, we rep...