LINC00460-miR-149-5p/miR-150-5p-Mutant p53 Feedback Loop Promotes Oxaliplatin Resistance in Colorectal Cancer

• Main Authors: Xiangfeng Meng (Author), Wu Sun (Author), Jing Yu (Author), Yu Zhou (Author), Yuanyuan Gu (Author), Jiayi Han (Author), Likun Zhou (Author), Xiaohong Jiang (Author), Chen Wang (Author)
• Format: Book
• Published: Elsevier, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Oxaliplatin resistance is a major challenge in the clinical treatment for advanced colorectal cancer (CRC). Long non-coding RNAs (lncRNAs) are involved in tumorigenesis and progression as critical regulators, while their potential roles in chemoresistance are poorly understood. In this study, we rep...