SMAD1 as a biomarker and potential therapeutic target in drug-resistant multiple myeloma

• Главные авторы: Jian Wu (Автор), Min Zhang (Автор), Omar Faruq (Автор), Eldad Zacksenhaus (Автор), Wenming Chen (Автор), Aijun Liu (Автор), Hong Chang (Автор)
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• Опубликовано: BMC, 2021-06-01T00:00:00Z.
• Предметы: article
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Abstract Background SMAD1, a central mediator in TGF-β signaling, is involved in a broad range of biological activities including cell growth, apoptosis, development and immune response, and is implicated in diverse type of malignancies. Whether SMAD1 plays an important role in multiple myeloma (MM)...